Product Name: RU58841; RU-58841
CAS: 154992-24-2
MF: C17H18F3N3O3
MW: 369.34
EINECS: 1592732-453-0
Boiling point: 493.6±55.0 °C(Predicted)
Density: 1.39
Storage temp.: Sealed in dry,Store in freezer, under -20°C
Solubility: DMF: 33 mg/ml; DMSO: 25 mg/ml; Ethanol: 33 mg/ml; Ethanol: PBS (pH 7.2) (1:5): 0.16 mg/ml
Appearance: White Powder
RU58841 is a non-steroidal selective androgen receptor modulator (SARM) that was initially developed as a treatment for prostate cancer. It is also known as PSK-3841 or HMR-3841. However, researchers later discovered that it could also be effective in treating hair loss.
RU58841 works by inhibiting the binding of dihydrotestosterone (DHT) to the androgen receptors in hair follicles.
Hair loss can be a distressing experience for anyone, especially if it happens at a young age. Many people resort to using hair loss treatments to regain their hair and prevent further hair loss.
RU58841 is one such treatment that has become increasingly popular in recent years.
DHT is a hormone that contributes to hair loss by causing miniaturization of hair follicles. By blocking the binding of DHT to the androgen receptors, RU58841 prevents the miniaturization of hair follicles and promotes hair growth.
A key difference is that RU58841 is topical, while FDA-approved finasteride is oral. There’s a topical version of finasteride, but it has yet to receive FDA approval. So, doctors can only prescribe oral finasteride at the moment.
Moreover, studies on RU58841 hair loss treatment only looked into its use on the scalp. Therefore, its known effects are only for scalp hair and not the hair on other body areas. That’s also why it doesn’t appear to affect DHT and testosterone in other body parts.
By contrast, oral finasteride increases the body’s total testosterone levels. As a result, it also decreases the size of the prostate, which is its first approved use.
There’s also a considerable difference between the RU58841 dose and that of finasteride. That’s because the recommended RU58841 dosage is 50 mg a day. By contrast, doctors can only prescribe 1 mg of finasteride a day to patients with pattern hair loss.
Finally, there’s the difference in the effects of RU58841 and finasteride. The findings of one study suggest that the former is more effective in suppressing DHT. Moreover, RU58841 influenced more hair follicles to shift into the anagen phase.
Now, keep in mind that the anagen phase is the growth phase of the hair growth cycle. Thus, the more follicles in the anagen phase, the more hair strands could grow. So, in that way, RU58841 may induce more hair growth than finasteride.
The typical dosage of RU58841 recommended is around 50 mg per day applied to the scalp, while the standard daily dosage of Finasteride for hair loss is 1 mg orally.
