Key Benefits of Anastrozole (Arimidex) Effective Estrogen Control: Anastrozole works by inhibiting the enzyme aromatase, which converts androgens into estrogen. This reduction in estrogen levels can help prevent estrogen-related side effects such as gynecomastia (breast tissue growth in men) and water retention. Breast Cancer Treatment: For postmenopausal women, Anastrozole is an effective treatment for hormone receptor-positive breast cancer. By lowering …